261 research outputs found

    Happiness Audit Among Female Students in a Higher Education Institution, Alagappa University, Karaikudi, India

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    Students can play an important role in improving and strengthening their society. During college, women gain vast amounts of knowledge and experience, and it also provides them with the best opportunity to prepare for their careers. Students are powerful human resources who are destined to decide the future of any country. In this modern era, the lives of students have become more competitive and they have become mere athletes in an academic race. There is an increased emphasis on measuring the talent of a student primarily through academic outcomes. The mental health of students is an important and necessary factor for achieving a better life, social welfare, and logical compatibility with life events. This fact must be given its due importance, but it is unfortunately completely ignored by manu institutions. From the above statements, it is clear that happiness plays a paramount role in the well-being of students. In this context, a happiness audit was conducted among female students pursuing higher education at Alagappa University in Karaikudi, India

    Formulation and Evaluation of Zolmitriptan

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    During past few decades, significant advance have been made in the area of controlled release as evidenced by an increasing number of patents, publication, as well as commercial controlled release products for the delivery of variety of pharmaceutical compounds1. With a controlled release formulation, predictable and reproducible release rate can be achieved, at the target site for desired duration. This results in optimum biological response, prolonged efficacy, decreased toxicity as well as reduction in required dose levels as compared to the conventional mode of delivery. Hydrophilic polymer matrix is widely used for formulating a controlled release dosage forms. The kinetic study was carried out for F14 formulation which showed that the drug release followed zero order kinetics followed by non-fickian diffusion. The stability studies were carried out for F14 formulation at 40o C / 75% RH for 3months. Data revelead that there was no considerable difference. From the above study, concluded that F14 was the optimized formulation, among all the formulation F14 formulation containing CAP+HPMC K15M 20% shows that 99% drug release at the end of 12hrs emerging as best formulation which followed by zero order release kinetics non fickian diffusion release

    Review Study on Larvicidal and Mosquito Repellent Activity of Volatile Oils Isolated from Medicinal Plants

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    Mosquito is a vector for serious human diseases like dengue fever, hemaorrhagic dengue fever and chikungunya, .yellow fever, malaria, filaria and encephalitis among these dengue, hemaorrhagic dengue and chikungunya are highly endemic diseases in Southeast Asian and African countries, causing millions of deaths each and every year. Mosquito repellents thus play a major role in preventing man-mosquito contact and there by minimize the chance of infections and its adverse effects. The development of resistance to chemical insecticides, results rebounding vectorial capacity. Synthetic repellents are chemicals which used worldwide for protection against mosquito-borne diseases and it adversely affects the environment by contaminating water, soil and air. There is an urgent need to find alternatives to the synthetic insecticides. Plants are rich source of alternative agents for control of mosquitoes and its vectors. Extracts and isolated compounds from different plant families have been evaluated for their promising larvicidal and mosquito repellent activities. Literature has documented that essential oils and extracts have been traditionally used as effective repellents. The essential oils whose repellent activities have been demonstrated, as well as the importance of the synergistic effects among their components are the main focus of this review study. Essential oils are volatile mixtures of hydrocarbons with a diversity of functional groups, and their repellent activity has been linked to the presence of monoterpenes and sesquiterpenes. The present review study focused the larvicidal potential and mosquito repellent activity of different volatile oils of medicinal plants. From an economical point of view synthetic chemical is still more frequently used as repellents than essential oils; these essential oils have the potential to provide efficient and can be used as a cheap, eco-friendly, safer for humans and the environment and also efficient alternative to the chemical larvicides

    Some results on best proximity pair theorems

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    [EN] Best proximity pair theorems are considered to expound the sufficient conditions that ensure the existence of an element xo ϵ A, such that d(xo; T xo) = d(A;B) where T : A 2B is a multifunction defined on suitable subsets A and B of a normed linear space E. The purpose of this paper is to obtain best proximity pair theorems directly without using any multivalued fixed point theorem. In fact, the well known Kakutani's fixed point theorem is obtained as a corollary to the main result of this paper.Srinivasan, P.; Veeramani, P. (2002). Some results on best proximity pair theorems. Applied General Topology. 3(1):25-32. doi:10.4995/agt.2002.2109SWORD25323

    On some fixed point theorems in Banach spaces

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    In this paper, some fixed point theorems are proved for multi-mappings as well as a pair of mappings. These extend certain known results due to Kirk, Browder, Kanna, Ćirić and Rhoades

    Software defined networking challenges and future direction: A case study of implementing SDN features on OpenStack private cloud

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    Cloud computing provides services on demand instantly, such as access to network infrastructure consisting of computing hardware, operating systems, network storage, database and applications. Network usage and demands are growing at a very fast rate and to meet the current requirements, there is a need for automatic infrastructure scaling. Traditional networks are difficult to automate because of the distributed nature of their decision making process for switching or routing which are collocated on the same device. Managing complex environments using traditional networks is time-consuming and expensive, especially in the case of generating virtual machines, migration and network configuration. To mitigate the challenges, network operations require efficient, flexible, agile and scalable software defined networks (SDN). This paper discuss various issues in SDN and suggests how to mitigate the network management related issues. A private cloud prototype test bed was setup to implement the SDN on the OpenStack platform to test and evaluate the various network performances provided by the various configurations

    The uniform boundedness theorem in asymmetric normed spaces

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    We obtain a uniform boundedness type theorem in the frame of asymmetric normed spaces. The classical result for normed spaces follows as a particular case.The authors are very grateful to the referee for many observations and comments that have allowed to improve the quality of the paper. The first two authors acknowledge the support of the Spanish Ministry of Science and Innovation under Grant MTM2009-12872-C02-01. The first author also acknowledges the support of the Spanish Ministry of Science and Innovation under Grant MTM2009-14483-C02-02.Alegre Gil, MC.; Romaguera Bonilla, S.; Veeramani, P. (2012). The uniform boundedness theorem in asymmetric normed spaces. Abstract and Applied Analysis. 2012:1-8. https://doi.org/10.1155/2012/809626S182012García-Raffi, L. M., Romaguera, S., & Sánchez-Pérez, E. A. (2002). Sequence spaces and asymmetric norms in the theory of computational complexity. Mathematical and Computer Modelling, 36(1-2), 1-11. doi:10.1016/s0895-7177(02)00100-0García-Raffi, L. M., & Sanchez-Pérez, R. (2003). The Dual Space of an Asymmetric Normed Linear Space. Quaestiones Mathematicae, 26(1), 83-96. doi:10.2989/16073600309486046Alegre, C., Ferrer, J., & Gregori, V. (1999). Acta Mathematica Hungarica, 82(4), 325-330. doi:10.1023/a:1006692309917Ferrer, J., Gregori, V., & Alegre, C. (1993). Quasi-uniform Structures in Linear Lattices. Rocky Mountain Journal of Mathematics, 23(3), 877-884. doi:10.1216/rmjm/1181072529Romaguera, S., & Sanchis, M. (2000). Semi-Lipschitz Functions and Best Approximation in Quasi-Metric Spaces. Journal of Approximation Theory, 103(2), 292-301. doi:10.1006/jath.1999.3439Alimov, A. R. (2001). Functional Analysis and Its Applications, 35(3), 176-182. doi:10.1023/a:1012370610709Rodríguez-López, J., Schellekens, M. P., & Valero, O. (2009). An extension of the dual complexity space and an application to Computer Science. Topology and its Applications, 156(18), 3052-3061. doi:10.1016/j.topol.2009.02.009Romaguera, S., Sánchez-Pérez, E. A., & Valero, O. (2006). The Dual Complexity Space as the Dual of a Normed Cone. Electronic Notes in Theoretical Computer Science, 161, 165-174. doi:10.1016/j.entcs.2006.04.031Romaguera, S., & Schellekens, M. P. (2002). Duality and quasi-normability for complexity spaces. Applied General Topology, 3(1), 91. doi:10.4995/agt.2002.2116Cobzaş, S. (2004). Separation of Convex Sets and Best Approximation in Spaces with Asymmetric Norm. Quaestiones Mathematicae, 27(3), 275-296. doi:10.2989/16073600409486100Alegre, C. (2008). Continuous operators on asymmetric normed spaces. Acta Mathematica Hungarica, 122(4), 357-372. doi:10.1007/s10474-008-8039-0Alegre, C., Ferrando, I., García-Raffi, L. M., & Sánchez Pérez, E. A. (2008). Compactness in asymmetric normed spaces. Topology and its Applications, 155(6), 527-539. doi:10.1016/j.topol.2007.11.004Borodin, P. A. (2001). Mathematical Notes, 69(3/4), 298-305. doi:10.1023/a:1010271105852García-Raffi, L. M. (2005). Compactness and finite dimension in asymmetric normed linear spaces. Topology and its Applications, 153(5-6), 844-853. doi:10.1016/j.topol.2005.01.014García-Raffi, L. M., Romaguera, S., & Sánchez-Pérez, E. A. (2009). The Goldstine Theorem for asymmetric normed linear spaces. Topology and its Applications, 156(13), 2284-2291. doi:10.1016/j.topol.2009.06.001Howes, N. R. (1995). Modern Analysis and Topology. Universitext. doi:10.1007/978-1-4612-0833-4Alegre, C., Ferrer, J., & Gregori, V. (1998). On a class of real normed lattices. Czechoslovak Mathematical Journal, 48(4), 785-792. doi:10.1023/a:102249992548

    Predicting functional associations from metabolism using bi-partite network algorithms

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    <p>Abstract</p> <p>Background</p> <p>Metabolic reconstructions contain detailed information about metabolic enzymes and their reactants and products. These networks can be used to infer functional associations between metabolic enzymes. Many methods are based on the number of metabolites shared by two enzymes, or the shortest path between two enzymes. Metabolite sharing can miss associations between non-consecutive enzymes in a serial pathway, and shortest-path algorithms are sensitive to high-degree metabolites such as water and ATP that create connections between enzymes with little functional similarity.</p> <p>Results</p> <p>We present new, fast methods to infer functional associations in metabolic networks. A local method, the degree-corrected Poisson score, is based only on the metabolites shared by two enzymes, but uses the known metabolite degree distribution. A global method, based on graph diffusion kernels, predicts associations between enzymes that do not share metabolites. Both methods are robust to high-degree metabolites. They out-perform previous methods in predicting shared Gene Ontology (GO) annotations and in predicting experimentally observed synthetic lethal genetic interactions. Including cellular compartment information improves GO annotation predictions but degrades synthetic lethal interaction prediction. These new methods perform nearly as well as computationally demanding methods based on flux balance analysis.</p> <p>Conclusions</p> <p>We present fast, accurate methods to predict functional associations from metabolic networks. Biological significance is demonstrated by identifying enzymes whose strong metabolic correlations are missed by conventional annotations in GO, most often enzymes involved in transport vs. synthesis of the same metabolite or other enzyme pairs that share a metabolite but are separated by conventional pathway boundaries. More generally, the methods described here may be valuable for analyzing other types of networks with long-tailed degree distributions and high-degree hubs.</p
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